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Our Data Access Request Management system and Portal will be down for scheduled maintenance from September 23rd, at 4 PM ET to September 27th, at 12 PM ET.IMPORTANT: eRA services such as logging in and authentication are currently unavailable due to maintenance. .DSS NIAGADS NIAGADS Data Sharing Service Apply/Access Data AboutData Summary Datasets Studies Cohorts Support Documentation FAQ Contact NewsNIAGADS Data Sharing Service The NIAGADS Data Sharing Service (DSS) is a repository that facilitates the deposition and sharing of genomic data from the ADSP and other NIA funded Alzheimer’s Disease and Related Dementias genomic studies with approved users in the research community. Latest Release: NG00161 – Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease – Eissman, et al. 2022 Application Instructions Data Submission Instructions Browse Datasets Open Access Datasets DSS Data Summary 103,721 subjects 448,147 files 1416.63 TB Total size DSS Data SummaryDSS File Types gVCFs 61,816 (42.77%) CRAMs 57,028 (39.46%) Phenotype Files 136 (0.09%) Genotype Files 24,886 (17.22%) Other Files 668 (0.46%) DSS File Typesx Browser Disclaimer NIAGADS DSS has been optimized for viewing in a common modern browser, i.e., Chrome 49+, Firefox 52+, Safari 10.1+ and Edge 14+. If you are running an older version or any other browser you may not be able to use all the features of our system.Latest News March 18, 2024 Creating the Largest Joint-Called Whole Exome Sequencing (WES) Dataset for Alzheimer’s Disease (AD) Over the last 20 years, the technology for DNA sequencing has rapidly evolved, making it possible to sequence individual whole genomes on a large scale. But when trying to find the underlying genetic causes of disease, every sequence donated matters. How can the sequences generated using older technology be reused?… Read more " about Creating the Largest Joint-Called Whole Exome Sequencing (WES) Dataset for Alzheimer’s Disease (AD) " February 9, 2024 15 Genotyping Array Datasets From the Alzheimer’s Disease Research Centers (ADRC) Now Available! We are thrilled to announce the release of 15 much-anticipated genotyping array datasets from participants recruited from the Alzheimer’s Disease Research Centers (ADRC)! These datasets, ADC1 through ADC15, are now available on the NIAGADS Data Sharing Service (DSS). DNA was prepared by the National Centralized Repository for Alzheimer’s Disease and… Read more " about 15 Genotyping Array Datasets From the Alzheimer’s Disease Research Centers (ADRC) Now Available!" January 5, 2024 Introducing hipFG: A high-throughput harmonization and integration pipeline for genomic annotations, QTLs, and chromatin interactions A major challenge facing researchers today is the cleanup and harmonization of data for use in their work. As datasets get larger and the types of outputs continue to grow, this problem will continue to grow exponentially. Manually cleaning this data can be time consuming and prone to human error. Addressing… Read more " about Introducing hipFG: A high-throughput harmonization and integration pipeline for genomic annotations, QTLs, and chromatin interactions" Disclaimer Privacy policy Acknowledgment Powered by:The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site © 2018 - 2024 University of Pennsylvania, School of Medicine. All rights...